The State Emergency Service issued the warning to Cowirra residents a short time ago.
“You need to evacuate now. If you do not evacuate you may be isolated or flooded. It may be too dangerous for emergency services to assist you,” it said in a statement.
The SES suggested residents stay with family, friends or alternate accommodation in areas unaffected by flooding.
Anyone unable to find accommodation can go to the Emergency Relief Centre at the Mannum Football Club, Belvedere Ave, Mannum, where support and emergency accommodation can be arranged.
The Burdett Road/Hunter Road junction at Mannum is now closed to all traffic.
This includes the closure of Burdett Road, from the junction to north of 2076 Burdett Road, Cowirra and Hunter Road, from the junction to just west of the East Front Road/Hunter Road junction.
A detour route connecting Burdett Road via Cross Road and Burt Road to the Hunter Road east of the Hunter Road/Burt Road junction has been installed.
As a result of this closure, the free Mannum passenger ferry service will stop from 12:30pm today.
The Department for Infrastructure and Transport is working with local operator, Four Knots Murray River Cruises, to ensure all passengers utilising the service reach their point of origin prior to its closure. Bus services supporting the ferry service will continue until after the last service.
Ferry services will recommence once water recedes, and a risk assessment has been completed to ensure it is safe.
The department also advised that Ferry Road, Wellington East, will be closed at 12pm today, Wednesday, 28 December due to rising water levels.
As a result, the Wellington Ferry will be closed with an alternative river crossing at the Tailem Bend Ferry.
Ferry Road and the Wellington Ferry will remain available for emergency and service authority vehicles.
The department is continuing to closely monitor water levels to keep ferries operating for as long as it is safe to do so, however some services may need to be closed at short notice.